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Finasteride hair loss female patients and to Diclofenac gel generika determine how the drug might affect development of prostate cancer." "The authors observed that Propecia decreases the incidence of prostate cancers in men with low to intermediate testosterone levels," says Dr. James R. Korn, M.D., Chairman of the Department Urology at Columbia University Medical Center in New York City. "Prostate cancer is already a common form of cancer, and as such, many physicians prescribe hormonal treatments," Korn adds. "The authors point out that the increased risk of prostate cancer may be due to the effect of high doses Propecia in reducing sperm counts. The adverse effect to other male reproductive organs associated with an increase in prostate size appears to predate the time of treatment, and authors cite animal studies showing that male animals exposed to increased amounts of prolactin for several weeks (as occurs with Propecia) may develop erectile dysfunction." The study, "Significant Effect of Prostate-Promoting Agents Luteinizing Hormone (LH) and Androstenedione the Prohormone Testosterone on Prostate Cancer Severity and Volume in Men," was funded, part, by Merck & Company Inc. "The authors reported that women with low to intermediate testosterone levels have the lowest risk of developing prostate cancer, but that the same effects are not seen in men with low testosterone levels," explains Dr. J. Eric Lothian, M.D., Director of Urology at Brigham and Women's Hospital. "There is currently no way to measure the levels of testosterone in body men, other than indirectly by monitoring sperm counts," says Lothian. "Because prostate gland function is intimately connected to many aspects of the physiology body, and also to the risk of prostate cancer, research into the mechanisms by which testosterone affects prostate cancer is essential." "If we do find that a drug increases the risk of prostate cancer by decreasing the volume of prostate, it can be potentially fatal," he adds. "In the case of Propecia, adverse effects were seen in the form of reduced volume, not in those with decreased testosterone levels." To be sure, some men with prostate cancer have low testosterone. "There are many types of prostate cancer, such that there are a multitude of mechanisms that contribute to a patient's cancer risk," says Lothian. And because the mechanisms are not fully clear, "it is clear why certain types of cancer are at higher risk for this disease." "However, the authors of recent study suggest that the increased risk of prostate cancer associated with an increase in testosterone may be due to the effects of high doses Propecia on sperm count by increasing the size of prostate and percentage the affected by disease—a process that causes a relative reduction in testosterone levels," Lothian adds. Korn stresses two other points in his review article, including the importance of understanding Finast 5mg $141.86 - $2.36 Per pill relative prostate volume versus the risk of prostate cancer between the various patient populations. He says, "This will help to establish the need for careful study of the effects prostate cancer on testosterone levels in men at risk," while still maintaining the importance of larger, more comprehensive studies showing that testosterone levels do not affect the risk of prostate cancer in a patient population of older men. "Anecdotally, men at the lower end of range testosterone levels often have prostate cancer," adds.
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